- Description:
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Description
A full read-out of the metabolome provides a wealth of information that can be used to identify metabolic profiles that predict disease risk, disease progression, and treatment outcome. Studies have shown that usually thousands of samples are necessary to find novel metabolic biomarker profiles, and even more for validation and replication. The number of samples increases even further when we want to identify early disease biomarkers using population-based metabolic profiling. To realise the potential of metabolomics for disease prediction and precision medicine, large-scale data acquisition is needed with sample sizes typically in the order of tens to hundreds of thousands. The analytical challenge posed by high-throughput metabolomics drives technological developments into the direction of more exhaustive analysis using smaller samples and shorter analysis times at a lower cost-per-sample.
We aim to set up a high-throughput, fully automated modular metabolomics lab including sample preparation, sample delivery, and data acquisition.
About Leiden University
Leiden University is one of Europe's foremost research universities. This prominent position gives our graduates a leading edge in applying for academic posts and functions outside academia. The university has legal personality under Dutch public law based upon article 1.8 of the Wet op het hoger onderwijs en wetenschappelijk onderzoek (Higher Education and Scientific Research Act).
About the Leiden Academic Centre for Drug Research
The Leiden Academic Centre for Drug Research (LACDR), part of the Faculty of Science, is a centre of excellence for multidisciplinary research on drug discovery and development. Within the LACDR, the research group Analytical Bioscience and Metabolomics, led by Prof. dr. Thomas Hankemeier, is part of the division of Systems Biomedicine and Pharmacology.
Procedure
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- Type:
- Sealed without Preselection
- Offer phase:
- 18 Feb 2021 17:00 — 1 Apr 2021 12:00
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